Completed Clinical Trials

The British Antibiotic and Silver-Impregnated Catheters for ventriculoperitoneal Shunts randomised controlled trial (BASICS)

Chief Investigators: Professor Conor Mallucci and Professor Michael Jenkinson

BASICS Trial SBNS-BASICS summary.jpg

An Evaluation of the Tolerability and Feasibility of Combining 5-Amino-Levulinic Acid (5-ALA) with BCNU Wafers in the Surgical Management of Primary Glioblastoma (GALA-5)

CI: Professor Colin Watts

GALA 5

Refining the Intraoperative Identification of Suspected High-Grade Glioma Using a Surgical Fluorescence Biomarker: GALA BIDD Study Report

Chief Investigator: Professor Colin Watts

GALA BIDD

SPRING Seizure prophylaxis in glioma (SPRING)

Chief Investigator: Professor Michael Jenkinson

Surgical microdiscectomy versus transforaminal epidural steroid injection in patients with sciatica secondary to herniated lumbar disc (NERVES)

Chief Investigator: Mr Martin Wilby

NERVES

Mobilisation versus no mobilisation in elderly patients with C2 fractures

Chief Investigator: Professor Paul Brennan

Randomised evaluation of surgery with craniectomy for uncontrollable elevation of intracranial pressure (RescueICP)

Chief Investigator: Professor Peter Hutchinson

RESCUEicp

Randomised Evaluation of Surgery with Craniectomy for patients Undergoing Evacuation of Acute Subdural Haematoma (RescueASDH)

Chief Investigator: Professor Peter Hutchinson

RescueASDH

Dexamethasone in Chronic SubDural Haematoma (Dex-CSDH)

Chief Investigator: Professor Peter Hutchinson

DEX- CSDH

International Subarachnoid Aneurysm Trial (ISAT) of neurosurgical clipping versus endovascular coiling in patients with ruptured intracranial aneurysms

Chief Investigator: Dr Andrew Molyneux

ISAT

Simvastatin in aneurysmal subarachnoid haemorrhage (STASH)

Chief Investigator Mr Peter Kirkpatrick

STASH

Completed Clinical Trials

To include SBNS Interpretation of the trial results

Hydrocephalus

The British Antibiotic and Silver-Impregnated Catheters for ventriculoperitoneal Shunts randomised controlled trial (BASICS)

Oncology

An Evaluation of the Tolerability and Feasibility of Combining 5-Amino-Levulinic Acid (5-ALA) with BCNU Wafers in the Surgical Management of Primary Glioblastoma (GALA-5)

Refining the Intraoperative Identification of Suspected High-Grade Glioma Using a Surgical Fluorescence Biomarker: GALA BIDD Study Report

SPRING Seizure prophylaxis in glioma (SPRING)

Spine

Surgical microdiscectomy versus transforaminal epidural steroid injection in patients with sciatica secondary to herniated lumbar disc (NERVES)

Mobilisation versus no mobilisation in elderly patients with C2 fractures

Trauma

Randomised evaluation of surgery with craniectomy for uncontrollable elevation of intracranial pressure (RescueICP)

Randomised Evaluation of Surgery with Craniectomy for patients Undergoing Evacuation of Acute Subdural Haematoma (RescueASDH)

Dexamethasone in Chronic SubDural Haematoma (Dex-CSDH)

Vascular

International Subarachnoid Aneurysm Trial (ISAT) of neurosurgical clipping versus endovascular coiling in patients with ruptured intracranial aneurysms

Simvastatin in aneurysmal subarachnoid haemorrhage (STASH)

Does Interleukin-1 Receptor Antagonist Improve Outcome following aneurysmal Subarachnoid Haemorrhage (aSAH)? A Phase III trial