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Become a Neurosurgeon

The management of neurosurgical patients requires excellent medical and surgical skills, a career in Neurosurgery offers many challenges and rewards.

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RECRUITING TRIALS                     

webpage_icon.gif DISCUS (CI- M Papadopoulos/ S Saadoun)

Duroplasty for Injured cervical Spinal Cord with Uncontrolled Swelling: a randomised controlled trial

     ENLIVEN-UK (CI - K Aqualina)

Neonatal IVH - endoscopic lavage

webpage_icon.gif FUTURE-GB (CIs - D Nandi/S Camp/P Plaha)

Adult RCT of intraoperative DTI navigation + intraoperative ultrasound versus standard care for pts undergoing tumour resection

webpage_icon.gif HIFU (CI Bojanic)

    High intensity focused ultrasound for primary sacrococcygeal bone tumours

Idiopathic Intracranial Hypertension (A Sinclair and G Tsermoulas)

webpage_icon.gif MAST (CI - P Hutchinson and A Kolias)

Pharmacological management of post-traumatic seizures

webpage_icon.gif POLYFIX (CI- M Kotter)

Posterior decompressive surgery with fixation for degenerative cervical myelopathy

RECEDE (CI - M Kotter)

Randomised, phase II trial to investigate feasibility, safety and regeneration-promoting effects of Ibudilast following surgical decompression in cervical degenerative myelopathy 

webpage_icon.gif ROAR (CI - D Bulters)

Risk of aneurysm rupture

SOS (CI - P Hutchinson and A Kolias)

Sugar or Salt: Hyperosmolar therapy in traumatic brain injury

webpage_icon.gif SCiL  (CI - A King) 

Interleukin-1 receptor antagonist in the treatment of aneurysmal subarachnoid haemorrhage

(recruitment complete - in follow up)


TRIALS IN SET UP

GO-SAH (CI- D Bulters)

Genetics of outcome after subarachnoid haemorrhage

Restart tICrH

Timing to restart direct oral anticoagulants in elderly TBI

SCARF-BT

Feasibility study on cognitive rehab in gliomas

STOP 'EM (CI - M Jenkinson)

Prophylactic trial for epilepsy in meningiomas

SWITCH

Surgery versus conservative treatment for spontaneous ICH

TOP-TBI (CI A Kolias and P Hutchinson)

Types and Timing of venous thromboembolism prophylaxis for traumatic brain injury

 

TRIALS IN FOLLOW UP / WRITE UP

webpage_icon.gif  ROAM  Liverpool (CI - M Jenkinson)webpage_icon.gif ISRCTN registry NIHR website

     Radiation versus observation following surgical resection of atypical meningiomas

 

CLOSED TRIALS 

DENS (CI - P Brennan)

Duration of External Neck Stabilisation following odontoid fracture in older or frail adults: a randomised controlled trial of collar versus no collar

 

 COMMERCIAL TRIALS

 webpage_icon.gif  PISCES II    webpage_icon.gif  ClinicalTrials.gov

 Phase II trial to determine whether it is sufficiently likely that CTX DP treatment at a dose level of 20million cells improves   recovery in the use of the paretic arm in acute stroke patients.

webpage_icon.gif  NOSTRA 11

 Randomised double blinded, placebo-controlled, prospective multicentre trial of NOSynthase inhibition in traumatic brain     injury

 

PUBLISHED TRIALS

pdf_icon.gif   STICH 1

pdf_icon.gif   STICH 11

pdf_icon.gif   STITCH Trauma  

pdf_icon.gif  STASH

webpage_icon.gif  Gala-5

pdf_icon.gif  EuroTherm

pdf_icon.gif  Rescue-ICP 

pdf_icon.gif  GALA-BIDD - Improving the intraoperative diagnosis of high-grade glioma using a flourescence biomarker

pdf_icon.gif  BASICS - British Antibiotic & Silver Impregnated Catheters for Ventriculoperitoneal Shunts Trial

     summary and interpretation of findings

pdf_icon.gif  NERVES  - Comparison of discectomy to injection for acute sciatica

     summary and interpretation of findings

pdf_icon.gif CENTER-TBI Collaborative European Neurotrauma Effectiveness Research in TBI

pdf_icon.gif DEX-CSDH - Randomised double blind, placebo controlled trial of dexamethasone for adult patients with symptomatic chronic subdural haematoma

webpage_icon.gif HTA website PRaM-GBM Predicting sites of treatment failure and tumour recurrence in the invasive margin of glioblastomas

pdf_icon.gif Rescue-ASDH - Randomised Evaluation of Surgery with Cranietomy for patients Undergoing Evacuation of Acute Subdural Haematoma

webpage_icon.gif  CARE ( CI - R Salman and N Kitchen)

Active versus conservative management of cavernomas

Last Updated: 24 May 2024