100,000 GENOMES PROJECT
Genomics England’s 100,000 Genome Project for Adult Primary Brain Tumours is now recruiting
Genomics England’s 100,000 Genome Project recently adapted adult primary brain tumours into its programme. This is a great opportunity to do whole genome sequencing for up to 1000 patients nationwide. All grades and types of gliomas are included as well as rarer intrinsic tumours such as embryonal tumours, pineal tumours, germ cell tumours and neuronal tumours. Participation and recruitment require collaboration between the neuro-oncology multidisciplinary team and its local Genomic Medical Centre. There are now 13 Genomic Medical Centres across England to cover this. The majority of the teaching hospitals will already have a dedicated 100,000 Genome Project team which will be the first point of contact to set up the local processes (including consent, tissue and data collection) as well as the link with the Genomic Medical Centres.
This is a unique opportunity to obtain large and comprehensive genomic and clinical data with the aim of translation into better patient care. I do hope that together we can take advantage of this.
Further information: Prof Keyoumars Ashkan (firstname.lastname@example.org)
Genomics England Clinical Interpretation Partnership Board Lead (Brain)
WELLCOME TRUST GRANT APPLICATIONS REQUIRE AN ORCiD
As of 1st August 2015 all researchers submitting a grant application to the Wellcome Trust must have an ORCiD (Open Researcher and Contributor ID). ORCiDs are a unique identifier for researchers and will differentiate you from other researchers with the same name. ORCiD IDs are linked to and increasingly required by many publishers, repositories and funders.
Further details are on the ORCiD website
LATEST RESCUE-ASDH NEWSLETTER
OPPORTUNITIES TO INFLUENCE HEALTH RESEARCH IN THE UK
NIHR research programme boards and panels select the most important research questions to commission and make funding recommendations on project applications.
They are looking for additional expertise for the boards or panels of the following programmes.
- Efficacy and Mechanism Evaluation (EME) Programme
- NIHR Health Services and Delivery Research (HD&SR) Programme
- NIHR Health Technology Assessment (HTA) Programme
Applications will open on 13 April 2015 and will close on 08 June 2015.
Further details and information on how to apply are available on the NIHR website
One of the available roles is for a Neurosurgeon with particular expertise in brain rather than spine (HTAP/15/16)
To serve as a member of the HTA Interventional Procedures Panel from November 2015 (possibly observe July 2015) for a term of two to four years. If you would like to discuss the role please contact Gaynor Young at email@example.com
RESEARCH DESIGN SERVICE (RDS)
The NIHR funds the RDS to provide design and methodological support to health and social care researchers across England to develop gran applications to the NIHR and other national peer-reviewed funding programmes.
Advice is confidential and free of charge Research Design Service
Latest bulletin from the RDS of the East of England
NIHR_RDS_East_of_England.pdf RDS East of England regional support 2015
ABSTRACT DEADLINE 1st JULY
Major International conference on Hydrocephalus in Bristol in September 2014. There will be many big name international speakers. This is great opportunity for trainees to get some financial support for educational/research activity and could fit well with other initiatives. Please see flyer. Hydrocephalus_2014.pdf
The last follow up for the RESCUE-icp trial is due in September
June 2014 The STASH paper has now been published in the Lancet Neurology -it can be currently accessed on line and will be in the July journal
LATEST NEWS ABOUT STASH
Recruitment to the STASH Trial has now closed, we have reached our target of 800 patients!!
The last 6 month follow up will be due in July, after which we plan to hold an Investigators Meeting later this year, to which all participating centres will be invited.
The STASH team would like to thank everyone who has supported us throughout and helped reach are target. It has been a pleasure working with you all.
AID TO ASSESSING TRIALS
The Dept of Neurosurgery at the general Infirmary Leeds (UK) has compiled an aid to assessing which patients are suitable for which Neurosurgical trials in the UK. Follow the link to view the document. www.leedsneurosurgery.com/trials
NEW CLINICAL TRIAL
We are pleased to announce that we have been awarded £2.04million from the NIHR HTA programme for the BASICS trial (see flyer).
This will be a national randomised shunt infection trial comparing Bactiseal, Silverline and standard catheters.
Funding is available for 14 centres (in addition to Liverpool) and the following sites have started preparation: Leeds, GOSH, Southampton, Oxford, Cardiff, Manchester, Newcastle, Nottingham, Cambridge.
The provisional trial start date is 1st December 2012
Chief Investigators: Conor Mallucci and Michael Jenkinson
Expressions of interest / enquiries welcome. Please contact the trial manager Tom Kearns or ourselves at the following email firstname.lastname@example.org
Conor Mallucci and Michael Jenkinson
Alder Hey and Walton Centre, Liverpool